Hydro Air Research Italia, in collaborative effort with international institutes and adsorbent manufacturer, built an expertise in designing process for different industrial chromatographic separations for molecules from antibiotics, natural active ingredients of plant origin, synthetic peptides, synthetic APIs, to macromolecules like enzymes, antibodies and plasmid DNA, DNA and RNA . Resins offered by Hydro Air Research Italia are rich in range of interactions as well as range of particle and pore sizes, they offer advantages like rigidity and stability to autoclaving and harsh CIP (cleaning in place) and SIP (sanitization in place) procedures.
Considerable work has lead Hydro Air Research Italia to design column hardware for both packed bed and expanded bed format of adsorption chromatography. Packed bed and expanded bed purification technologies have been developed for molecules from penicillin G, rifamycin, vitamin B12, and ?-carotene to proteins like lactoferrin, lactoperoxidase, lysozyme, insulin etc. Hydro Air Research Italia offers laboratory scale to plant scale column chromatography setups complete with column, pumps, piping system and measurements & controls.
Hydro Air Research Italia is also proposing of a new variant of expanded bed adsorption that attempts to overcome all disadvantages of packed bed and expanded bed operations.